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Nanoantibiotics capable of destroying harmful bacteria in the body

Despite advances in science, many ailments remain incurable today, with or without treatment. At the same time, some people are developing resistance to conventional antibiotics. It is surely for this reason that recently researchers have invented a new technology to solve this problem. Test phases are still in progress, but the results remain very promising.

In fact, it would be nanoantibiotics developed by an expert in physiology and biophysics molecular. The challenge was to create nanoparticles capable of targeting and destroying harmful bacteria, while sparing healthy cells. To do this, the hydrophobic properties of the latter were exploited.

The expert in physiology and molecular biophysics Hongjun Liang is the biologist behind this incredible invention. The latter was supported by his colleagues from the Texas Tech University Health Sciences Center.

The use of nanoparticles, a very brilliant idea

Indeed, the main goal of the research carried out was to create nanoparticles with the ability to discern the Pathogens healthy cells, as do antimicrobial peptides. To do this, studies were undertaken on the capacities hydrophobic and hydrophilic cells.

According to these investigations, the more hydrophobic a substance, the more detrimental these effects are. This finding prompted Liang to say ScienceDaily that the higher the hydrophobicity, the more bacteria can be killed effectively. However, the corresponding effect also targets healthy cells. In order to solve this problem, Liang and his team had to rethink the physical design of this nanotechnology.

As a result, the developed nanoparticles were very similar to tiny hairy spheres equipped with hydrophilic polymer brushes embedded with nanoparticles of silica. The process will thus target only the bacterial membranes and spare healthy cells.

More than promising results

In reality, nanoantibiotics are not unstable and toxic, unlike the antimicrobial peptides ordinary. According to expert Liang, these problems have been solved by the use of polymers hydrophilic as alternatives. Moreover, he explained that the nanoparticles of silica do not kill bacteria, but with the good grafting on the nanostructure, they will be able to do so.

He declared: “Discovery is the most essential aspect for the development of the study of nanoantibiotics. »

Being proud of the results of his invention, the expert added: “all the findings mentioned in their research could serve as a model for creating new antibiotics that will be cordial to the natural protectors of the human system, as they come from environmentally friendly and non-toxic compositions via nano-engineering. »

SOURCE: SCIENCETIMES

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